SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

SBIR · Phase: Phase II · Topic PAR-27-098 · Solicitation PAR-27-098

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs (also known as America's Seed Fund) are major sources of early-stage funding for U.S. technology development and commercialization. NIH SBIR and STTR awards support projects through multiple phases: Phase I: Establish the technical merit and feasibility of the proposed R&D. Phase II: Continue R&D to advance toward commercialization. After Phase II, NIH expects small business concerns (SBCs) to fully commercialize the product or technology using non-SBIR/STTR funds (federal or non-federal). However, biomedical projects often need specialized studies or product development services (for example, market research) to commercialize or attract third-party investment. This additional work is often outsourced to contract research organizations (CROs). Some NIH Institutes, Centers, and Offices (ICOs) participate in the Phase IIB Strategic Breakthrough program PA-27-101, which provides a second Phase II award to help bridge this gap, but those awards limit the amount of work that can be outsourced and require matching funds. What this NOFO Supports The Commercialization Readiness Pilot (CRP) NOFO provides later-stage research and development and technical assistance to NIH SBIR or STTR Phase II recipients. The CRP program can support R&D that requires significant outsourcing and/or is needed during an active Phase II awards. This funding opportunity requires a prior (active or ended) NIH Phase II award. New SBIR Phase I and II grant applications should be submitted to PA-27-100 and STTR Phase I and II grant applications should be submitted to PA-27-102. Phase II recipients that need significant R&D funding to bridge the gap between the SBIR or STTR Phase II award and commercialization should consider the Phase IIB Strategic Breakthrough. See PA-27-101. Applicants are strongly encouraged to contact program staff prior to applying to help choose the best funding opportunity for their project. Note: This NOFO accepts New "Type 1" Applications from recipients of NIH SBIR or STTR Phase II awards or an NIH SBIR or STTR Phase IIB Strategic Breakthrough award. SBCs must meet the eligibility requirements in Section III. Scientific/Technical Scope SBCs may propose to do technical assistance, later-stage R&D activities, or both in the application. Applications from eligible United States SBCs should propose a technical assistance and/or a R&D study that contributes to the missions of any NIH components participating in this NOFO. See NIH Institutes, Centers, and Offices and Small Business Funding Considerations and Contacts for Institute, Center, and Office (ICO) specific missions, interest areas, funding priorities, and funding considerations. Some examples of activities within scope include (but are not limited to): Technical Assistance: Regulatory strategy and submissions Intellectual property (IP) strategy Manufacturing technical assistance Other third-party technical assistance (e.g. market research) Late Stage Research and Development Activities: Independent replication or confirmation of key studies. Development and optimization or manufacturing methods. Activities to bring development under Design and Quality Systems Control. Device, Drug, and Biologic-related pre-clinical product development. Clinical studies and clinical trials (Note: Not every NIH participating component accepts clinical trials through this NOFO. See "Applications Not Responsive to this NOFO" below.) Outsourcing and project oversight Applicants may outsource a significant portion of CRP work. The expert services should fit the work proposed and be well justified in the application. The SBC must perform a substantial role in oversight and management of the proposed work, which should be reflected in the budget. This includes appropriate oversight of all scientific, programmatic, financial, and administrative matters related to the grant. Costs and requests not allowed CR…

SBIR/STTR 은 미국 중소기업만 지원할 수 있습니다(Small Business Act 법정 요건). • 계열사를 포함해 상시 종업원 500명 이하 • 미국 시민 또는 영주권자 1인 이상이 50%를 초과해 직접 소유·지배 • 미국 내 사업장을 두고 주로 미국 내에서 사업을 영위할 것 • 수행책임자(PI)의 주된 근무처가 신청 기업일 것 출처: https://www.sbir.gov/faq/eligibility-requirements

Primary country

🇺🇸 United States

Also eligible

None

Foreign companies

No

Local entity

Required

Location condition

미국 내 사업장을 두고 미국 시민·영주권자가 50%를 초과해 소유한 중소기업만 신청할 수 있습니다(법정 요건).

Document requirements were not captured (needs verification). Check the official announcement.

Application process not captured.

Evaluation process not captured.

Process steps were not captured.

Generated by local:rules-v1 · 3h ago

The announcement does not say what has to be submitted, so the disclosure exposure cannot be judged. the scope of the material requested is not stated. The awarding body is U.S. Department of Health and Human Services. 8 fields could not be read and must be checked in the announcement and the grant agreement.

This assessment is derived from the stored announcement, document and contract fields. Anything the source does not state is marked "needs verification" — it never asserts that your idea will be taken. Generated by local:rules-v1 · 3h ago

Official URL

https://simpler.grants.gov/opportunity/ed6db6b2-d74e-4838-9223-ce72f4895688

Application URL

https://simpler.grants.gov/opportunity/ed6db6b2-d74e-4838-9223-ce72f4895688

Last fetched

2026.08.20

Human review

Not reviewed — check the official announcement

First seen

2026.08.20

Data status

Auto-collected, not reviewed

AI enrichment

local:rules-v1 · 3h ago