Development of devices, diagnostic technologies, or digital health tools for treatment, detection, and diagnosis of Pediatric Cancers and/or Rare Cancers.

SBIR · Phase: Phase I · Topic 2 · Solicitation 75N98026R00109

About 9,550 children in the United States under the age of 15 will be diagnosed with cancer in 2025 (https://www.cancer.org/cancer/cancer-in-children/key-statistics.html). Cancer is the leading cause of death from disease in children ages 1 to 14 in the US after infancy. Similarly, as a group, rare cancers are the leading cause of cancer deaths in the United States (https://rarecancer.org/). For the purposes of this solicitation, a rare cancer is defined in accordance with the U.S. Food and Drug Administration (FDA) Orphan Drug Act as a malignancy with a total U.S. prevalence of fewer than 200,000 individuals. Prevalence estimates should be supported by authoritative data sources (e.g., SEER) or where direct estimates are not available, by scientifically justified epidemiologic approximations based on published literature. This definition is intended to capture clinically and biologically relevant rare cancer populations that may not be fully represented in existing rare disease databases. Applications must clearly describe how the proposed technological approach has the potential to result in a meaningful improvement in patient survival and/or to address areas of significant unmet medical need where the current standard of care has demonstrated limited progress. Access the NCI Surveillance, Epidemiology, and End Results Program (SEER) database (https://seer.cancer.gov/) for more information regarding 5-year cancer survival rates. Because of smaller patient populations and challenging development pathways, development of new technologies focused on pediatric and rare cancers lag significantly compared to other major cancers. Innovative and transformative solutions focused on prevention, diagnosis, detection, and treatment in both pediatric cancers and rare cancers are urgently needed. Rather than just the tried and tested approaches that have not led to much success and progress, bold and “out of the box” ideas that are still based on sound scientific premise are needed to make a significant impact in the prevention, diagnosis, treatment, and care of patients with pediatric and/or rare cancer. Thus, the NCI SBIR Development Center has developed the NCI SBIR Innovative Concept Award program to encourage the development of high-risk innovative and disruptive technologies. The Concept Award program will provide funding to small businesses to explore the technical feasibility and demonstrate proof of concept for the development of highly innovative therapies, devices, diagnostic tools, or preventive strategies focused on pediatric and rare cancers. The focus is on innovation and “out of the box” ideas that have not been tried and tested before. So, preliminary data is not required; however, proposed ideas should have sound scientific premise either based on the offeror’s own research or referenced literature evidence. Offerors are eligible to apply if they have disruptive ideas based on sound scientific premise with a potential to make an impact in these cancers. The goal of the funding is for offerors to generate de-risking technical data that provides key proof of concept validation. We also want the offerors to explore the commercial potential and development path of the technology during the award period. In addition to funding, the program will also provide additional business and commercialization resources including entrepreneurship training to explore and refine the business model and commercialization plan. Activities and deliverables proposed by the offerors would differ based on their technology types and stage of development. However, the offerors should ensure that they clearly identify the clinical problem and cancer type(s) that the proposal will focus on with adequate justification. In addition, the offerors should propose experiments to obtain initial de-risking and proof-of-concept data and at the completion of the project present a report with the results of the experiments to the NCI. Examples of activities an…

SBIR/STTR 은 미국 중소기업만 지원할 수 있습니다(Small Business Act 법정 요건). • 계열사를 포함해 상시 종업원 500명 이하 • 미국 시민 또는 영주권자 1인 이상이 50%를 초과해 직접 소유·지배 • 미국 내 사업장을 두고 주로 미국 내에서 사업을 영위할 것 • 수행책임자(PI)의 주된 근무처가 신청 기업일 것 출처: https://www.sbir.gov/faq/eligibility-requirements

Primary country

🇺🇸 United States

Also eligible

None

Foreign companies

No

Local entity

Required

Location condition

미국 내 사업장을 두고 미국 시민·영주권자가 50%를 초과해 소유한 중소기업만 신청할 수 있습니다(법정 요건).

Document requirements were not captured (needs verification). Check the official announcement.

Application process not captured.

Evaluation process not captured.

Process steps were not captured.

Generated by local:rules-v1 · 4h ago

The announcement does not say what has to be submitted, so the disclosure exposure cannot be judged. the scope of the material requested is not stated. The awarding body is U.S. Department of Health and Human Services — NIH. 8 fields could not be read and must be checked in the announcement and the grant agreement.

This assessment is derived from the stored announcement, document and contract fields. Anything the source does not state is marked "needs verification" — it never asserts that your idea will be taken. Generated by local:rules-v1 · 4h ago

Official URL

https://sam.gov/workspace/contract/opp/8fbf26c5215646f582bf9fe4b4f00fca/view

Application URL

https://sam.gov/workspace/contract/opp/8fbf26c5215646f582bf9fe4b4f00fca/view

Last fetched

2026.08.20

Human review

Not reviewed — check the official announcement

First seen

2026.08.20

Data status

Auto-collected, not reviewed

AI enrichment

local:rules-v1 · 4h ago